1. Indicate the right answer
Metabolite of ketone bodiesoxiditation resulting from the following reaction
CH3-CHOH-CH2-COOH + NAD+
A. acetoacetic acid
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-glutaryl-CoA
2. Indicate the right answer
Metabolite of ketone bodies oxiditation resulting from the following reaction
CH3-CO-CH2-COOH+ATP+HS-CoA
A. acetoacetic acid.
B. β-hydroxy-β-methylglutaryl-CoA
C. acetyl-CoA
D. β-hydroxy-β-glutaryl-CoA
E. acetoacetyl-CoA
3. Indicate the right answer
Metabolite of ketone bodies oxiditation resulting from the following reaction
CH3-CO-CH2-COOH+ HOOC-CH2-CH2-CO-S-CоA
A. acetoacetic acid
B. β-hydroxy-β-methylglutaryl-CoA
C. acetyl-CoA
D. β-hydroxy-β-glutaryl-CoA
E. acetoacetyl-CoA
4. Indicate the right answer
Metabolite of ketone bodies oxiditation resulting from the following reaction
CH3-CO-CH2-CO-S-COA+HS-CoA
A. acetoacetic acid
B. β-hydroxy-β-methylglutaryl-CoA
C. acetyl-CoA
D. β-hydroxy-β-glutaryl-CoA
E. acetoacetyl-CoA
5. Compare the names of the metabolites of ketone bodiesoxiditationto their formulas
CH3-CO-S-CoA
A. β-hydroxy-β-methylglutaryl-CoA
B. β-hydroxy-β-glutaryl-CoA
C. acetoacetyl-CoA
D. acetyl-CoA
E. β-hydroxybutyrate
6. Compare the names of the metabolites of ketone bodies oxiditation to their formulas
CH3-CHOH-CH2-COOH
A. β-hydroxy-β-methylglutaryl-CoA
B. β-hydroxy-β-glutaryl-CoA
C. acetoacetyl-CoA
D. acetyl-CoA
E. β-hydroxybutyrate
7. Compare the names of the metabolites of ketone bodies oxiditation to their formulas
CH3-CO-CH2-COOH
A. acetoacetyl-CoA
B. acetyl-CoA
C. β-hydroxybutyrate
D. β-hydroxy-β-methylglutaryl-CoA
E. acetoacetic acid
8. Compare the names of the metabolites of ketone bodies oxiditation to their formulas
CH3-CO-CH2-CO-S-CoA
A. acetoacetyl-CoA
B. acetyl-CoA
C. β-hydroxybutyrate
D. β-hydroxy-β-methylglutaryl-CoA
E. acetoacetic acid
9. Match the following
Compare the names of the metabolites of ketone bodiesoxidation to their formulas
1. CH3-CO-CH2-CO-S-CoA A. β-hydroxy-β-methylglutaryl-CoA
2. CH3-CO-S-CoA B. acetyl-CoA
C. β-hydroxybutyrate
D.acetoacetyl-CoA
10. Match the following
Compare the names of the metabolites of ketone bodies oxidation to their formulas
1. CH3-CO-CH2-COOH A. β-hydroxy-β-methylglutaryl-CoA
2. CH3-CHOH-CH2-COOH B. acetyl-CoA
C. β-hydroxybutyrate
D. acetoacetyl-CoA
E. acetoacetic acid
11. Match the following
Compare the names of the metabolites of ketone bodies oxidation to their formulas
1. CH3-CO-CH2-CO-S-CoA A. β-hydroxy-β-methylglutaryl-CoA
2. CH3-CO-CH2-COOH B. acetyl-CoA
C. β-hydroxybutyrate
D. acetoacetyl-CoA
E. acetoacetic acid
12. Indicate the correct answer
The enzymewhich catalyzes the oxidation of ketone bodies
CH3-CO-CH2-COOH+ATP+HS-CoA
A. acetoacetyl-CoA thiolase
B. β-hydroxysteroiddehydrogenase
C. succinyl-CoA-acetoacetate-transferase
D. HMG-CoA lyase
E. acyl-CoA synthatase
13. Indicate the correct answer
The enzyme which catalyzes the oxidation of ketone bodies
CH3-CO-CH2-COOH+HOOC-CH2-CH2-CO-S-CoA
A. acetoacetyl-CoA thiolase
B. β-hydroxysteroiddehydrogenase
C. succinyl-CoA-acetoacetate-transferase
D. HMG-CoA lyase
E. acyl-CoA synthatase
14. Indicate the correct answer
The enzyme which catalyzes the oxidation of ketone bodies
CH3-CO-CH2-CO-S-CoA+HS-CoA
A. acetoacetyl-CoA thiolase
B. β-hydroxysteroiddehydrogenase
C. succinyl-CoA-acetoacetate-transferase
D. HMG-CoA lyase
E. acyl-CoA synthetase
15. Arrange in the correct sequence
Metabolites of ketone bodiesoxidation
A. CAC
B. acetoacetyl-CоA
C. acetyl-CоA
D. β-hydroxybutyrate
E. acetoacetic acid
16. Arrange in the correct sequence
Metabolites of ketone bodies oxidation
A. CAC
B. CH3-CO-CH2-CO-S-CoA
C. CH3-CO-S-CoA
D. CH3-CHOH-CH2-COOH
E. CH3-CO-CH2-COOH
17. Select the desired object in the picture
Indicate the ATP-dependent reaction in the process of ketone bodiesofoxidation
CH3-CHOH-CH2-COOH
1 β-hydroxybutyrate
CH3-CO-CH2-CO-S- CoA
2 acetoacetyl-CоA
CH3-CO-S-CoA
3 acetyl - CoA
CAC
18. Select the desired object in the picture
Indicate the reaction catalyzed by acetoacetate transferase in the process of ketone bodiesoxidation
CH3-CHOH-CH2-COOH
1 β-hydroxybutyrate
CH3-CO-CH2-CO-S- CoA
2 acetoacetyl-COA
CH3-CO-S-CoA
3 acetyl - CoA
CAC
19. Select the desired object in the picture
Indicate the reaction of acetoacetic acid formation in the process of ketone bodies oxiditation
CH3-CHOH-CH2-COOH
CH3-CO-CH2-CO-COOH
CH3-CO-CH2-CO-S-CoA
CH3-CO-S-CoA
СAC
20. Select the desired object in the picture
Indicate the reaction of acetyl-CoAof formation in the process of ketone bodies oxiditation
CH3-CHOH-CH2-COOH
CH3-CO-CH2-CO-COOH
CH3-CO-CH2-CO-S-CoA
CH3-CO-S-CoA
CAC
21. Indicate the right answer
Metabolite of ketone bodiesynthesis resulting from the following reaction
CH3-CO-S-CoA+CH3-CO-S-CoA
A. β-hydroxy-β-glutaryl-CоA
B. acetoacetyl-CоA
C. acetyl-CоA
D. mevalonic acid
E. β-hydroxy-β-methylglutaryl-CоA
22. Indicate the right answer
Metabolite of ketone bodie synthesis resulting from the following reaction
CH3-CO-CH2-CO-S-CoA +NADPHH+
A. β-hydroxy-β-glutaryl-CоA
B. acetoacetyl-CоA
C. acetyl-CоA
D. mevalonic acid
E. β-hydroxy-β-methylglutaryl-CоA
D. β-hydroxy-β-methylglutaryl-CoA
23. Indicate the right answer
Metabolite of ketone bodie synthesis resulting from the following reaction
CH3-CO-S-CoA + CH3-CO-S-CoA
A. CH3-CHOH-CH2-COOH
B. HOOC-CH2-C(OH)-CH2-CO-S-CoA
C. CH3-CO-CH2-CO-S-CoA
D. CH2OH-CHOH-CH2OH
E. CH3-CO-S-CoA
24. Indicate the right answer
Metabolite of ketone bodie synthesis s resulting from the following reaction
CH3-CO-CH2-COOH + NADPHH+
A. CH3-CHOH-CH2-COOH
B. HOOC-CH2-C(OH)-CH2-CO-S-CoA
C. CH3-CO-CH2-CO-S-CoA
D. CH2OH-CHOH-CH2OH
E. CH3-CO-S-CoA
25. Indicate the right answer
Metabolite of ketone bodie synthesis the formula of which is shown in the picture
CH3-CO-S-CoA
A. mevalonic acid
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-lglutaryl-CoA
26. Indicate the right answer
Metabolite of ketone bodie synthesis the formula of which is shown in the picture
CH3-CO-CH2-CO-S-CoA
A. mevalonic acid
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-lglutaryl-CoA
27. Indicate the right answer
Metabolite of ketone bodie synthesis the formula of which is shown in the picture
CH3-CHOH-CH2-COOH
A. β-hydroxybutyrate
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-glutaryl-CoA
27. Match the following
Compare the names of the metabolites of ketone bodies synthesis to their formulas
1. CH3-CO-S-CoA A. β-hydroxybutyrate
2. CH3-CO-CH2-CO-S-CoA B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-glutaryl-CoA
28. Match the following
Compare the names of the metabolites of ketone bodies synthesis to their formulas
1. CH3-CHOH-CH2-COOH A. β-hydroxybutyrate
2. CH3-CO-CH2-CO-S-COA B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-glutaryl-CoA
29. Indicate the right answer
The enzyme catalyzing the given reactionin the process of ketone bodiessynthesis
CH3-CO-S-CoA + CH3-CO-S-CoA
A. HMG-CoA lyase
B. acetyl-CoA-acetyltransferase
C. β-hydroxysteroiddehydrogenase
D. HMG-CoA synthase
E. diglyceride-acyltransferase
30. Indicate the right answer
The enzyme catalyzing the given reaction in the process of ketone bodies synthesis
CH3-CO-CH2-CO-S-CoA + CH3-CO-S-CoA
A. HMG-CoA lyase
B. acetyl-CoA-acetyltransferase
C. β-hydroxysteroiddehydrogenase
D. HMG-CoA synthase
E. diglyceride-acyltransferase
31. Indicate the right answer
The enzyme catalyzing the given reaction in the process of ketone bodies synthesis
CH3-CO-CH2-CO-S-COA+ NADPHH+
A. HMG-CoA lyase
B. acetyl-CoA-acetyltransferase
C. β-hydroxysteroiddehydrogenase
D. HMG-CoA synthase
E. diglyceride-acyltransferase
32. Arrange in the correct sequence the metabolites of ketone bodiessynthesis
A. β-hydroxybutyrate
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
33. Select the desired object in the picture
The reaction catalyzed by acetyl-CoA acetyltransferase in the process of ketone bodiessynthesis
34. Select the desired object in the picture
The reaction catalyzed by HMG-CoA – lyase in the process of ketone bodies synthesis
35. Select the desired object in the picture
The reaction catalyzed by β-hydroxybutyrate dehydrogenase in the process of ketone bodiessynthesis
36. Select the desired object in the picture
The reaction of β-hydroxybutyrate dehydrogenasedegradationin the process of ketone bodiessynthesis
37. Indicate the right answer
Metabolite of cholesterol synthesis resulting from the following reaction
CH3-CO-S-CoA+CH3-CO-S-CoA
A. mevalonic acid
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-lglutaryl-CoA
38. Indicate the right answer
Metabolite of cholesterol synthesis resulting from the following reaction
CH3-CO-CH2-CO-S-CoA + CH3-CO-S-CoA
A. mevalonic acid
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-lglutaryl-CoA
39. Indicate the right answer
Metabolite of cholesterol synthesis resulting from the following reaction
CH3-CO-S-CoA + CH3-CO-S-CoA
A. mevalonic acid
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-lglutaryl-CoA
40. Metabolite of cholesterol synthesis, the formula of which is shown in the picture
CH3-CO-S-CoA
A. mevalonic acid
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-lglutaryl-CoA
41. Metabolite of cholesterol synthesis, the formula of which is shown in the picture
CH3-CO-CH2-CO-S-CoA
A. mevalonic acid
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-lglutaryl-CoA
42. Match the following
Compare the names of the metabolites of cholesterol synthesis to their formulas
1. CH3-CO-S-CoA
2. CH3-CO-CH2-CO-S-CoA A. mevalonic acid
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. β-hydroxy-β-lglutaryl-CoA
43. Indicate the right answer
The enzyme catalyzing the given reaction of cholesterol synthesis
CH3-CO-S-CoA + CH3-CO-S-CoA
A. HMG-CoA synthase
B. HMG-CoA reductase
C. diglyceride-acyltransferase
D. thiolase
E. phosphatidycholine
44. Indicate the right answer
The enzyme catalyzing the given reaction of cholesterol synthesis
CH3-CO-CH2-CO-S-CoA + CH3-CO-S-CoA
A. HMG-CoA synthase
B. HMG-CoA reductase
C. diglyceride-acyltransferase
D. thiolase
E. phosphatidycholine
45. Arrange in the correct sequence the metabolites of cholesterol synthesis
A. cholesterol
B. acetoacetyl-CoA
C. acetyl-CoA
D. β-hydroxy-β-methylglutaryl-CoA
E. mevalonic acid
F. squalene
G. lanosterol
46. Select the desired object in the picture
NAD+ dependent response of cholesterol synthesis
Acetyl - CoA
1
Acetoacetyl - CoA
2
HMG - CoA
3
Mevalonate
47. Select the desired object in the picture
The reaction catalyzed by HMG-CoA synthase in cholesterol synthesis
Acetyl - CoA
1
Acetoacetyl - CoA
2
HMG - CoA
3
Mevalonate
48. Determineand specify the enzyme, which activity is inhibited by cholesterol
A. acetyl CoA- transferase
B. acetyl CoA- decarboxylate
C. oxidometylglutaryl CoA-reductase
D. acetyl Coa-acetyltransferase
49. Indicate the right answer
All the metabolites formed during the synthesis of cholesterol and ketone bodies
A. mevalonic acid
B. acetoacetyl -CoA
C. acetoacetic acid
D. β-hydroxy-β-methylglutaryl-CoA
50. Cholesterol in the cells of the adrenal cortex is used for the biosynthesis of….
A. Corticosteroids
B. Bile acids
C. Vitamin D3
D. sex hormones
E. insulin
51. Cholesterol in the cells of sex hormones is used for the biosynthesis of
A. Corticosteroids
B. Bile acids
C. Vitamin D3
D. sex hormones
E. insulin
52. Cholesterol in the liver cells is used for the biosynthesis of………
A. Corticosteroids
B. Bile acids
C. Vitamin D3
D. sex hormones
E. insulin
53. Cholesterol in the skin cells is used for the biosynthesis of………..
A. Corticosteroids
B. Bile acids
C. Vitamin D3
D. sex hormones
E. insulin
54. Match the followingwith the main transport form
Lipids Transport form
1. triacylglycerol formed in
the enterocytes A. CM
2. triacylglycerol formed in B. LDL
the hepatocytes C. VLDL
D. HLD
E. CE
55. Match the following lipids with the main form of transport
Lipids The main form of transport
1. triacylglycerol formed in A. LDL
the hepatocytes B. CM
2. cholesterol C. VLDL
3. triacylglycerol formed in D. HLD
the enterocytes
56. Match the following
Transport form of lipids synthesis
1. LDL A. liver
2. CM B. blood
3. VLDL C. intestinal mucosa
4. HLD D. erythrocytes
57. Match the following
Cholesterol transport Transport form
1. in tissue A. LDL
2. from tissue B. CM
C. VLDL
D. HLD
58. Insert theright answer (write it down)
Two moles of acetyl Co A are condensed with the formation of (......). This product coudenses with another molecule of acetyl Co A, to form (.......), that is broken down into acetyl Co A and (......), which can be ather reduced into (......), then decarboxylation into (........).
59. Specify the transport form of ketone bodies
A. bound to albumin
B. free
C. VLDL
D. HLD
60. The precursor for the ketone bodiessynthesis is
A. fatty acid
B. glucose
C. acyl-CoA
D. malonyl-CoA
E. succinyl-CoA
61. Phospholipids are
A. esters of glycerol and fatty acids
B. esters of glycerol, fatty acids, phosphoric acid and nitrogenous bases
C. esters of cholesterol and fatty acids
62. Common metabolite of triacylglycerols and phospholipidssynthesis is
A. dioxyacetone
B. 3- phosphoglycerol aldehyde
C. phosphatidic acid
D. 2 monoacylglycerol
E. 1.2 -diacylglycerol
63. Phosphatidylethanolamineis formed by condensation of diacylglycerol and
A. ethanolamine
B. phosphoethanolamine
C. AMP-ethanolamine
