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Metabolism of triacylglycerols




1. Indicate the right answer

Name the product of the followingreaction:

CH2OH-CHOH-CH2OH + ATP

A. dioxyacetonephosphate

B. glycerol

C. phosphatidic acid

D. diglyceride

E. glycerol-3-phosphate

 

2. Indicate the right answer

Name the product of the following reaction:

CH2OH-CO-CH2OPO3H2 + NADHH+

A. dioxyacetonephosphate

B. glycerol

C. phosphatidic acid

D. diglyceride

E. glycerol-3-phosphate

 

3. Indicate the right answer

Name the product of the following reaction:

CH2OH-CHOH-CH2OPO3H2 + R1-CO-S-CoA + R2-CO-S-CoA

A. dioxyacetonephosphate

B. glycerol

C. phosphatidic acid

D. diglyceride

E. glycerol-3-phosphate

 

4. Indicate the right answer

Name the product of the following reaction:

CH2OH- CO- CH2OP3H2 + NADHH+

A. CH2OH- CHOH- CH2OP3H2

B. CH2OH- CO- CH2OP3H2

C. CH2OH-CHOH-CH2OH

 

5. Indicate the right answer

Name the following structure:

CH2OH-CHOH-CH2OH

A. dioxyacetonephosphate

B. glycerol

C. phosphatidic acid

D. diglyceride

E. glycerol-3-phosphate

 

6. Indicate the right answer

Name the following structure:

CH2OH-CO-CH2OPO3H2

A. dioxyacetonephosphate

B. glycerol

C. phosphatidic acid

D. diglyceride

E. glycerol-3-phosphate

 

7. Indicate the right answer

Name the following structure:

CH2OH-CHOH-CH2OPO3H2

A. dioxyacetonephosphate

B. glycerol

C. phosphatidic acid

D. diglyceride

E. glycerol-3-phosphate

 

8. Match the following

Name the following structure:

1. CH2OH-CO-CH2OPO3H2 A. dioxyacetonephosphate

2. CH2OH-CHOH-CH2OH B. glycerol

C. phosphatidic acid

D. diglyceride

E. glycerol-3-phosphate

 

9. Match the following

Name the following structure:

1. CH2OH-CHOH-CH2OPO3 A. dioxyacetonephosphate

2. CH2OH-CHOH-CH2OH B. diglyceride

C. phosphatidic acid

D. glycerol

E. glycerol-3-phosphate

 

10. Indicate the right answer

Name the enzyme catalyzing the following reaction

CH2OH-CHOH-CH2OH + ATP

A. diglyceride-acyltransferase

B. PCAT

C. glycerolphosphate-acyltransferase

D. glyсerol-3- phosphate dehydrogenase

E. glycerol kinase

 

11. Indicate the right answer

Name the enzyme catalyzing the following reaction

CH2OH-CHOH-CH2OPO3H2+ NADHH+

A. diglyceride-acyltransferase

B. PCAT

C. glycerolphosphate-acyltransferase

D. glyсerol-3- phosphate dehydrogenase

E. glycerol kinase

 

 

12. Indicate the right answer

Which enzyme catalyzes the given reaction of triglyceride synthesis

CH2OH-CHOH-CH2OPO3H2 + R1-CO-S-CoA + R2-CO-S-CoA

A. diglyceride-acyltransferase

B. phosphatidecholine

C. glycerolphosphate-acyltransferase

D. gliсerolphosphatdegidrogenazy

E. glycerokinase

 

13. Arrange the following in the correct sequence

Metabolites of triglyceride synthesis

A. glycerides

B. glycerin

C. phosphatidic acid

D. diglycerides

E. glycerol-3-phosphate

 

14. Indicate the right answer

Metabolite of fatty acid synthesis results from this reaction

CH3-CO-S-CoA+ HS-ACP

A. malonyl- ACP

B. acetyl-APB

C. malonyl-CoA

D. acyl-CoA

E. acetyl-CoA

15. Indicate the right answer

Metabolite of fatty acid synthesis resulting from this reaction

HOOC-CH2-CO-S-CoA+HS- ACP

A. malonyl-ACP

B. acetyl-ACP

C. malonyl-CoA

D. acyl-CoA

E. acetyl-CoA

 

16. Indicate the right answer

Metabolite of fatty acid synthesis resulting from this reaction

CH3-CO-S- ACP + HOOC-CH2-CO-S- ACP

A. malonyl-ACP

B. acetyl-ACP

C. malonyl-CoA

D. acyl-CoA

E. acetoacetyl-ACP

 

17. Indicate the right answer

Metabolite of fatty acid synthesis resulting from this reaction

CH3-CO-CH2-CO-S- ACP + NADPHH+

A. malonyl-ACP

B. acetyl-ACP

C. malonyl-CoA

D. acetoacetyl-ACP

E. β-hydroxybutyryl-ACP

 

18. Indicate the right answer

Metabolite of fatty acid synthesis resulting from this reaction

CH3-CH(OH)-CH2-CO-S- ACP

A. crotonyl-ACP

B. malonyl-ACP

C. acetyl-ACP

D. acetoacetyl-ACP

E. β-hydroxybutyryl-ACP

 

19. Indicate the right answer

Metabolite of fatty acid synthesis resulting from this reaction

CH3-CH=CH-CO-S- ACP + NADPHH+

A. crotonyl-ACP

B. malonyl-ACP

C. acetoacetyl-ACP

D. β-hydroxybutyryl-ACP

E. butyryl-ACP

 

20. Indicate the right answer

Metabolite of fatty acid synthesis resulting from this reaction

CH3-CO-S-CoA+ HS- ACP

A. CH3-CO-S- ACP

B. HOOC-CH2-CO-S-CoA

C. CH3-CO-CH2-CO-S-APB

D. CH3-CH(OH)-CH2-CO-S-APB

E. HOOC-CH2-CO-S- ACP

 

21. Indicate the right answer

Metabolite of fatty acid synthesis formula of which is shown in the picture

CH3-CO-S-ACP

A. malonyl-ACP

B. acetyl-ACP

C. malonyl-CoA

D. acyl-CoA

E. acetyl-CoA

 

22. Indicate the right answer

Metabolite of fatty acid synthesis formula of which is shown in the pictureHOOC-CH2-CO-S-CoA

A. malonyl-ACP

B. acetyl-ACP

C. malonyl-CoA

D. acyl-CoA

E. acetyl-CoA

 

 

23. Indicate the right answer

Metabolite of fatty acid synthesis formula of which is shown in the picture

HOOC-CH2-CO-S- ACP

A. malonyl-ACP

B. acetyl-ACP

C. malonyl-CoA

D. acyl-CoA

E. acetyl-CoA

 

24. Indicate the right answer

Metabolite of fatty acid synthesis formula of which is shown in the picture

CH3-CO-CH2-CO-S- ACP

A. crotonyl-ACP

B. malonyl-ACP

C. acetoacetyl-ACP

D. β-hydroxybutyryl-ACP

E. butyryl-ACP

 

25. Match the following

Compare the names of the metabolites of fatty acid synthesiswithto their formulas

 

1. HOOC-CH2-CO-S-CoA A. malonyl-ACP

2. CH3-CO-S-APB B. acetyl-ACP

C. malonyl-CoA

D. acyl-CoA

E. acetyl-CoA

26. Match the following

Compare the names of the metabolites of fatty acid synthesis with to their formulas

1. CH3-CO-S-CoA A. malonyl-ACP

2. CH3-CO-S- ACP B. acetyl-ACP

C. malonyl-CoA

D. acyl-CoA

E. acetyl-CoA

 

27. Indicate the right answer

The enzyme catalyzing thegiven of fatty acids synthesis

CH3-CO-S-CoA + HS-ACP

A. acetyltransacylase

B. β-hydroxyacyl-ACP-dehydrogenese

C. β-ketoacyl-malonyl-ACB-reductase

D. acyl-malonyl-ACP

E. malonyl-transacylase

 

28. Indicate the right answer

The enzyme catalyzing the given of fatty acids synthesis

HOOC-CH2-CO-S-CoA + HS-ACP

A. acetyltransacylase

B. β-hydroxyacyl-ACP-dehydrogenese

C. β-ketoacyl-malonyl-ACB-reductase

D. acyl-malonyl-ACP

E. malonyl-transacylase

29. Indicate the right answer

The enzyme catalyzing the given of fatty acids synthesis

CH3-CO-S-ACP + HOOC-CH2-CO-S-CoA

A. acetyltransacylase

B. β-hydroxyacyl-ACP-dehydrogenese

C. β-ketoacyl-malonyl-ACB-reductase

D. acyl-malonyl-ACP

E. malonyl-transacylase

 

30. Indicate the right answer

The enzyme catalyzing the given of fatty acids synthesis

HOOC-CH2-CO-S-CoA + NADPHH+

A. enol-ACP-reductase

B. β-hydroxyacyl-ACP-dehydrogenese

C. β-ketoacyl-ACB-reductase

D. acyl-malonyl-ACP

E. malonyl-transacylase

 

31. Indicate the right answer

The enzyme catalyzing the given of fatty acids synthesis

CH3-CH=CH-CO-S-ACP - H2O

A. enol-ACP-reductase

B. β-hydroxyacyl-ACP-dehydrogenese

C. β-ketoacyl-ACB-reductase

D. acyl-malonyl-ACP

E. malonyl-transacylase

 

32. Indicate the right answer

The enzyme catalyzing the given of fatty acids synthesis

CH3-CH=CH-CO-S-ACP + NADPHH+

A. acyl-malonyl-ACP

B. malonyl-transacylase

C. β-hydroxyacyl-ACP-dehydrogenese

D. enol-ACP-reductase

E. β-ketoacyl-ACB-reductase

 

33. Arrange in the correct sequence

The metabolites of fatty acid synthesis (starting with acetyl-CoA)

A. malonyl-ACP + acetyl-ACP

B. crotonyl-ACP

C. acetoacetyl-ACP

D. acetyl-ACP

E. β-hydroxyacyl-ACP

F. malonyl-ACP

 

34. Arrange in the correct sequence

The metabolites of fatty acid synthesis (starting with acetyl-CoA)

A. CH3-CO-S-ACP + HOOC-CH2-CO-S-CoA

B. CH3-CH2-CH2-CO-S-ACP

C. CH3-CH(OH)-CH2-CO-S- ACP

D. CH3-CO-S-CoA

E. HOOC-CH2-CO-S-CoA

F. CH3-CH=CH-CO-S-ACP

G. CH3-CO-CH2-CO-S-ACP

 

35. Select the desired object in the picture

Mark the ATP-dependent reaction of fatty acid synthesis

 

HOOC-CH2-CO-S-CoA 2 CH3-CO-S-CoA

3 1

HOOC-CH2-CO-S-ACP 4 CH3-CO-S-ACP

 

CH3-CO-CH2-CO-S-ACP

CH3-CH(OH)-CH2-CO-S-ACP

6

CH3-CH=CH-CO-S-ACP

7

CH3-CH2-CH2-CO-S-ACP

 

 

36. Select the desired object in the picture

Mark the NADPHH+ dependent reaction of fatty acid synthesis

 

HOOC-CH2-CO-S-CoA 2 CH3-CO-S-CoA

3 1

HOOC-CH2-CO-S-ACP 4 CH3-CO-S-ACP

 

CH3-CO-CH2-CO-S-ACP

CH3-CH(OH)-CH2-CO-S- ACP

6

CH3-CH=CH-CO-S-ACP

7

CH3-CH2-CH2-CO-S-ACP

 

37. Select the desired object in the picture

Mark the reaction catalyzed by β-ketoacyl-ACP-reductase in the synthesis of fatty acids

 

HOOC-CH2-CO-S-CoA 2 CH3-CO-S-CoA

3 1

HOOC-CH2-CO-S-ACP 4 CH3-CO-S-ACP

 

CH3-CO-CH2-CO-S-ACP

CH3-CH(OH)-CH2-CO-S-ACP

6

CH3-CH=CH-CO-S-ACP

7

CH3-CH2-CH2-CO-S-ACP

 

38. Select the desired object in the picture

Mark the reaction catalyzed by β -ketoacyl-ACP- reductase in the synthesis of fatty acids

 

HOOC-CH2-CO-S-CoA 2 CH3-CO-S-CoA

3 1

HOOC-CH2-CO-S-ACP 4 CH3-CO-S-ACP

 

CH3-CO-CH2-CO-S-ACP

CH3-CH(OH)-CH2-CO-S-ACP

6

CH3-CH=CH-CO-S-ACP

7

CH3-CH2-CH2-CO-S-ACP

 

39. Select the desired object in the picture

The reaction of acetyl-ACP formation in the the synthesis of fatty acids

HOOC-CH2-CO-S-CoA 2 CH3-CO-S-CoA

3 1

HOOC-CH2-CO-S-ACP 4 CH3-CO-S-ACP

 

CH3-CO-CH2-CO-S-ACP

CH3-CH(OH)-CH2-CO-S-ACP

6

CH3-CH=CH-CO-S-ACP

7

CH3-CH2-CH2-CO-S-ACP

 

40. Indicate the right answer

Metabolite of fatty acid oxidation resulting from the following reaction

R-COOH + HS-CoA+ATP

A. carnitine

B. acetyl-CoA

C. acyl-CoA

D. acylcarnitine

E. enoyl-CoA

 

41. Indicate the right answer

Metabolite of fatty acid oxidation resulting from the following reaction

R-CH2-CH2-CoA~S-CoA+FAD+

A. carnitine

B. acetyl-CoA

C. acyl-CoA

D. acylcarnitine

E. enoyl-CoA

 

42. Indicate the right answer

Metabolite of fatty acid oxidation resulting from the following reaction

R-CH(OH)-CH2-CO~S-CoA+NAD+

A. acetyl-CoA

B. acyl-CoA

C. β-ketoacyl-CoA

D. enoyl-CoA

E. β-hydroxyacyl-CoA

 

43. Indicate the right answer

Metabolite of fatty acid oxidation resulting from the following reaction

R-CO-CH2-CO~S-CoA+HS-CoA

A. acetyl-CoA

B. acyl-CoA

C. enoyl-CoA

D. β-hydroxyacyl-CoA

E. acylcarnitine

 

44. Indicate the right answer

Metabolite of fatty acid oxidation resulting from the following reaction

R-CO-CH2-CO~S-CoA+ HS-CоA

A. R-CH(OH)-CH2-CO~S-CoA

B. R-CO-CH2-CO~S-CoA

C. CH3-CO-S-CoA

D. R-CO-S-CoA

E. R-CH=CH-CO~S-CoA

 

45. Indicate the right answer

Metabolite of fatty acid oxidation formulaof which is shown in the picture

R-COOH

A. acylcarnitine

B. acetyl-CoA

C. fatty acid

D. carnitine

E. acyl-CoA

 

46. Indicate the right answer

Metabolite of fatty acid oxidation formula of which is shown in the picture

R-CO~S-CoA

A. acylcarnitine

B. acetyl-CoA

C. fatty acid

D. carnitine

E. acyl-CoA

 

47. Indicate the right answer

Metabolite of fatty acid oxidation formula of which is shown in the picture

R-CH=CH-CO~S-CoA

A. carnitine

B. acyl-CoA

C. acylcarnitine

D. acetyl-CoA

E. enoyl-CoA

 

48. Indicate the right answer

Metabolite of fatty acid oxidation formula of which is shown in the picture

R-CH2-CH2- CO~S-CoA

A. carnitine

B. acyl-CoA

C. acylcarnitine

D. acetyl-CoA

E. enoyl-CoA

 

 

48. Indicate the right answer

Metabolite of fatty acid oxidation formula of which is shown in the picture

R-CH(OH)-CH2-CO-S-CoA

A. acetyl-CoA

B. enoyl-CoA

C. carnitine

D. β-hydroxyacyl-CoA

E. acyl-CoA

 

49. Indicate the right answer

Metabolite of fatty acid oxidation formula of which is shown in the picture

R-CH=CH-CO-S-CoA

A. acetyl-CoA

B. enoyl-CoA

C. carnitine

D. acylcarnitine

E. acyl-CoA

 

50. Indicate the right answer

Metabolite of fatty acid oxidation formula of which is shown in the picture

CH3-CO-S-CoA

A. enoyl-CoA

B. β-hydroxyacyl-CoA

C. acetyl-CoA

D. carnitine

E. β-ketoacyl-CoA

 

51. Match the following

Compare the names of the metabolites of fatty acid oxidation to their formulas

1. R-CO~S-CoA A. fatty acid

2. R-COOH B. carnitine

C. acyl-CoA

D. β-hydroxyacyl-CoA

E. enoyl-CoA

 

52. Match the following

Compare the names of the metabolites of fatty acid oxidation to their formulas

1. R-CH(OH)-CH2-CO~S-CoA A. acyl-CoA

2. R-CH=CH-CO~S-CоA B. β-hydroxyacyl-CoA

C. enoyl-CoA

D. fatty acid

E. β-ketoacyl-CoA

 

53. Match the following

Compare the names of the metabolites of fatty acid oxidation to their formulas

1. R-CO-CH2-CO~S-CoA A. acyl-CoA

2. R-CH=CH-CO~S-CoA B. β-hydroxyacyl-CoA

C. enoyl-CoA

D. fatty acid

E. β-ketoacyl-CoA

 

54. Indicate the right answer

Name the enzyme catalyzing the following reaction

R-COOH+HS-CoA+ATP

A. acyl-CoA-isomerase

B. acyl-CoA-transferase

C. acyl-CoA-dehydrogenase

D. acyl-CoA-synthase

E. carnitine-acyl-CoA-transferase

 

55. Indicate the right answer

Name the enzyme catalyzing the following reaction

R-CH2-CH2- CO~S-CoA + FAD+

A. acyl-CoA-isomerase

B. acyl-CoA-transferase

C. acyl-CoA-dehydrogenase

D. acyl-CoA-synthase

E. carnitine-acyl-CоA-transferase

 

56. Indicate the right answer

Name the enzyme catalyzing the following reaction

R-CH=CH-CO~S-CoA + H2O

A. enoyl-CoA-hydrotase

B. acyl-CoA-transferase

C. acyl-CoA-dehydrogenase

D. acyl-CoA-synthase

E. carnitine-acyl-CoA-transferase

 

57. Indicate the right answer

Name the enzyme catalyzing the following reaction

R-CH(OH)-CH2-CO~S-CoA + NAD+

A. acyl-CoA-hydrotase

B. enoyl-CoA-hydrotase

C. 3-hydroxi-CoA-dehydrogenase

D. acyl-CoA-synthase

E. carnitine-acyl-CoA-transferase

 

58. Indicate the right answer

Name the enzyme catalyzing the following reaction

R-CO-CH2-CO~S-CoA + HS-CoA

A. enoyl-CoA-hydrotase

B. ketoacyl-CoA-acyltransferase

C. acetyl-CoA-acyltransferase

D. acyl-CoA-synthase

E. carnitine-acyl-CoA-transferase

 

59. Arrange in the correct sequence

Metabolites of fatty acids oxiditation (starting with the activation of the fatty acid)

A. acyl-CoA

B. acylcarnitine

C. fatty acid

D. β-hydroxyacyl-CoA

E. enoyl-CoA

F. β-ketoacyl-CoA

 

60. Select the desired object in the picture

The ATP-dependent reaction of fatty acid oxidation

Fatty acid

 
 


Acyl-CoA

2

Acylcarnitine

3

Acyl-CoA

4

Enoyl-CoA

5

β-hydroxyacyl-CoA

6

β-ketoacyl-CoA

       
   
 


Fumarate 7 8 Acetyl-CoA

 

61. Select the desired object in the picture

The FAD-dependent reaction of fatty acid oxidation

Fatty acid

 
 


 

Acyl-CoA

2

Acylcarnitine

3

Acyl-CoA

4

Enoyl-CoA

5

β-hydroxyacyl-CoA

6

β-ketoacyl-CoA

       
   
 


Fumarate 7 8 Acetyl-CoA

 

62. Select the desired object in the picture

The NAD-dependent reaction of fatty acid oxidation

 

R-COOH

R-CH2-CH2-CO-S-CoA

2

R-CH2-CH2-CO-S-CoА

3

R-CH=CH-CO-S-CoA

4

R-CH(OH)-CH2-CO-S-CoA

5

R-CO-CH2-CO-S-CoA

6

R-CH2-CH2-CO-S-CoA + CH3-CO-S-CoA

63. Select the desired object in the picture

The reaction of enoyl-CoA formation in the process of fatty acid oxiditation

R-COOH

R-CH2-CH2-CO-S-CoA

2

R-CH2-CH2-CO-S-CoА

3

R-CH=CH-CO-S-CoA

4

R-CH(OH)-CH2-CO-S-CoA

5

R-CO-CH2-CO-S-CoA

6

R-CH2-CH2-CO-S-CoA + CH3-CO-S-CoA

 

64. Select the desired object in the picture

The reaction catalyzed by acyl-CoA-syntetase during the process of fatty acid oxiditation

 

R-COOH

R-CH2-CH2-CO-S-CoA

2

R-CH2-CH2-CO-S-CoА

3

R-CH=CH-CO-S-CoA

4

R-CH(OH)-CH2-CO-S-CoA

5

R-CO-CH2-CO-S-CoA

6

R-CH2-CH2-CO-S-CoA + CH3-CO-S-CoA

 

65. Select the desired object in the picture

The reaction catalyzed by acyl-CoA –dehydrogenase during the process of the fatty acid oxiditation

 

R-COOH

1

R-CH2-CH2-CO-S-CoA

2

R-CH2-CH2-CO-S-CoА

3

R-CH=CH-CO-S-CoA

4

R-CH(OH)-CH2-CO-S-CoA

5

R-CO-CH2-CO-S-CoA

6

R-CH2-CH2-CO-S-CoA + CH3-CO-S-CoA

 

 





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