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( ) . - -. 25 43 12 8 , , , . ( ) ( ) -. . , - -, .
( 125 )
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( EIS)
33- 187 , () 3- 47 1- 15 1989 , (). 33- (61%) 1 15 , . ( , ) , , , . ( [] = 15.5, 95%- [] = 2.59-92.51). , , ( = 5.67, 95%- = 0.98-32.65), ( = 4.50, 95%- = 0.48-62.76) ( = 4.50, 95%- = 0.37-54.4). , - , - .
( 175 )
( EIS)
() , . FDA, . 1985 30 000 ; 90% -. 25% . 20% . . .
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( 100 )
: - . , - " " - .
( " ")
, , , , . , . , . , .
( 100 )