() , (93,9 100 . ) (84,4) , (77,8) ( 81,0; 79,2; 72,7). ( 32,4). , . 34,2-37,3 100 . . 28 %, 2,81 % [2, 5].
, , , , , , ( BRCA 1 BRCA 2) [5].
2- :
1. (, , , );
2. :
) ;
) ;
) ;
) /
;
)
( ).
3. :
)
)
)
)
)
)
)
) , .
( , NM-, 5- , 1997 .)
-
- .
0 - .
is - .
1 - 2 .
T1mic 0,1 .
1 - 0,5 .
1 - 1 .
1 - 2 .
2 - 5 .
3 - 5 .
4 - ( , , , ).
4a - .
4b - , , , .
|
|
|
4c , 4a 4b.
4d - .
N - (. 1)
N - .
N0 - .
N1 () .
N2 , , .
.
N3 .
-
- .
0 - .
1 - ( ).
:
| PUL | BRA | MAR | PER | ||||
| OSS | LYM | PLE | SKI | ||||
| HEP | OTH |
Gx - .
G1 .
G2 .
G3 .
G4 .
| 0 | is | N0 | 0 |
| I | 1 | N0 | 0 |
| II | 0 | N1 | 0 |
| 1 | N1 | 0 | |
| 2 | N0 | 0 | |
| II | 2 | N1 | 0 |
| 3 | N0 | 0 | |
| III | 0 | N2 | 0 |
| 1 | N2 | 0 | |
| 2 | N2 | 0 | |
| 3 | N2 | 0 | |
| III | 4 | N | 0 |
| N3 | 0 | ||
| IV | N | 1 |
|
( in situ) / ( ) [3, 5, 9]. , :
