1. : (MAP-microtubuls-associated proteins)
2. .
MAP ,
MAP .
+TIPS - (+)- , , , . +TIPS (+)-, , XMAP215 (+)- .
CLASP - (+)- . - (+)- .
- +TIP (+)- . GTP (MCAK - , (+)- ).
- , . . .
- (+)-.
MAP , .
I MAP KKEX (Lys-Lys-Glu-X) (-)- .
II MAP . 3-4 18 , .
(+)- :
1. APC, Kar9 (Sc)*
2. APC (adenomatous polyposis coli) - , b-.
3. EB1, Bim1(Sc), Mal3 (Sp)
4. EB1 (end-binding protein 1) - APC.
5. Nud (An)
6. Nud (nuclear distribution) - .
7. Lis1/NUDF (An), Pac1 (Sc)
8. Lis (lissencephaly) - ( ).
9. .
10. NUDE (An), R011 (Neurospora crassa)/Ndl1 (Sc); Nde1, Ndel(). Lis1 .
11. Kar3 (Sc)
12. Kar3 - , C- Kinesin-14.
13. Kip2(Sc), Tea2 (Sp), KipA (An)
a. Kinesin-7 :
14. CENP-E - , Kip2, Tea2 and
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15. KipA
16. Klp10A (Dm), Klp59C, MCAK
Kinesin-13. Klp10A - Kif2A . Klp59C (Dm) -
MCAK . KLP10A Kin I (-)- . , ( ).
Dynactin
p150glued. , . p150glued - NUDMA. nidulans.
CLIP-170, Bik1 (Sc), Tip(Sp)
CLIP-170 , .
LIP-170 - -, , .
LIP-170 N- - . N- (+)- , C- - p150Glued, . -
, :
1. - , .
2. . .
3. - -.
4. - .
5. , , , .
6. - .