Method and route of Administration

№ 1

Экзаменационная аннотация на лекарственный препарат для перевода без словаря по дисциплине «Английский язык»

(итоговый контроль 2 курс)

IMUDON

Trade name: IMUDON

Dosage form: sucking tablets.

Composition

The drug is a polyvalent antigenic complex, a mixture of bacterial lysates, whose composition corresponds to that of the pathogens that more often cause inflammatory processes in the oral cavity and throat.

Description

White or almost white planocylindrical tablets with a smooth luster surface, without pores.

Pharmacotherapeutical group Immunostimulant.

Pharmacological properties A bacterial immunostimulant for local use in dentistry and otolaryngology.

Activates phagocytosis, promotes the increase in the count of immunocompetent cells, enhances the production of lysozyme and interferon, salivary secretary immunoglobulin A.

Indications

Treatment and (or) prevention of inflammatory and infectious oral and pharyngeal diseases:

•pharyngitis;

•chronic tonsillitis;

•oral dysbacteriosis;

•erythematous and ulcerative gingivitis;

•ulcerations caused by dentures.

Contraindications

•individual hypersensitivity to the active ingredient or

any other components of the product;

•children under 3 years of age.

Pregnancy and lactation

Information on the use of Imudon in pregnant females is insufficient. There are no relevant data of animal experiments and epidemiological studies. The use of Imudon is not recommended during pregnancy and lactation.

Dosage and administration

For adults and adolescents above 14 years In acute and inflammatory diseases of the oral cavity and throat and exacerbations of chronic diseases the drug should be used as 8 tablets daily. The tablets should be sucked (without chewing) in the oral cavity at an interval of 1 hour. The mean duration of a therapy course is 10 days.

For the prevention of chronic inflammatory diseases of the oral cavity and throat, the drug should be used as 6 tablets daily. The tablets should be sucked (without chewing) in the oral cavity at an interval of 2 hours. The duration of a course is 20 days. Three-four annual courses of preventive Imudon therapy are recommended.

For children aged 3 to 14 years

For the treatment of acute and recurrent chronic inflammatory diseases of the oral cavity and throat and for their prevention, the drug should be used as 6 tablets daily. The tablets should be sucked (without chewing) in the oral cavity at an interval of 2 hours. The duration of a therapy course for acute diseases is 10 days, that for the prevention of chronic diseases is 20 days.

Three-four annual courses of preventive therapy with the drug are recommended.

Adverse reactions

In rare cases the use of the drug may cause allergic reactions (eruption, urticaria, angioneurotic edema). There may be gastrointestinal reactions (nausea, vomiting, abdominal pain).

Overdosage

Cases of IMUDON overdosage have not been described.

Drug interactions

IMUDON may be used in combination with drugs from other groups.

Special instructions

Children aged 3 to 6 years are to suck the tablets in the oral cavity under adult control!

If required, the mouth should be gargled not earlier than 1 hour after the use of IMUDON not to reduce the therapeutic activity of the drug.

When the drug is prescribed to patients on a salt-free or restricted diet, it should be taken into account that 1 tablet of IMUDON contains 15 mg of sodium.

Effect on the capacity of driving a car and handling with other mechanisms

There are no data suggesting that the activities associated with the driving of a car or handling with other mechanisms should be limited during treatment.

Pack

A blister contains 8 tablets. A cardboard pack contains 5 blisters.

Storage

The drug should be stored at a temperature of not above 25 C. To keep out of the reach of children!

Denture dentures– вставные челюсти

№ 2

(итоговый контроль 2 курс)

DUSPATALIN

Trade name: Duspatalin®

DOSAGE FORM:

Prolonged-release capsules

COMPOSITION:

Active ingredient: Each retard capsule contains 200 mg of mebeverine hydrochloride.

Excipients: Magnesium stearate; metacryl acid copolymer; talc; hypromelloze; methylhydroxypropyl-cellulose, methacryl and ethacryl acid copolymer; glycerol triacetate; hard gelatin capsule: gelatin, titanium dioxide.

DESCRIPTION:

Hard white opaque gelatin capsules No. 1 with «245» imprinted on the shell of a capsule and with «S» and «V» on its cap. The contents of the capsules are white or almost white granules.

PHARMACOTHERAPEUTIC GROUP:

Spasmolytic.

PHARMACOLOGICAL ACTION:

This is a myotropic spasmolytic that directly affects the smooth muscles of the gastrointestinal tract (chiefly the large bowel). It eliminates spasm, without exerting any effect on normal intestinal motility. The drug has no anticholinergic activity.

PHARMACO-KINETICS:

When orally used, duspatalin undergoes presystemic hydrolysis and it is undetectable in the plasma. The drug is hepatiсаllу metabolized to veratric acid and mebeverine alcohol. It is mainly excreted by kidneys as metabolites, in small quantities by bile. Mebeverine capsules have the properties of prolonged release. Significant accumulation of the drug does not occur even after its multiple use.

INDICATIONS:

Gastrointestinal spasm (including that caused by an organic disease), intestinal colic, biliary colic, irritable colon syndrome.

Children aged above 12 years

Gastrointestinal functional disorders accompanied by abdominal pain.

CONTRAINDICATIONS:

Hypersensitivity to any components of the drug.

PREGNANCY AND LACTATION:

Animal experiments have revealed no teratogenic effect of the drug. However, it is necessary to compare maternal benefits with potential fetal risks when the drug is administered to pregnant women. When administered in therapeutic doses, mebeverine does not penetrate into breast milk so this drug may be used during lactation.

DOSAGE AND ADMINISTRATION

The drug should be swallowed whole by taking with water.

A capsule (200 mg) should be orally taken 20 minutes before a

meal twice a day (in the morning and in the evening).

ADVERSE REACTIONS

Dizziness has been rarely observed. In extremely rare cases, there may be following hypersensitivity reactions: urticaria, Ouincke's edema, facial edema, and exanthema.

OVERDOSAGE

Theoretically, there may be occasionally hyperexcitability of the central nervous system. The specific antidote of the drug is unknown. Gastric lavage and symptomatic treatment are recommended.

PRECAUTIONS

During therapy, caution should be exercised while driving motor-vehicle transport and being engaged in the potentially dangerous activities that require increased attention concentration and rapid psychomotor reactions.

DOSAGE FORM

200-mg prolonged-release capsules. 10 capsules in a blister made from aluminum foil and PVC film. 2 or 3 blisters are placed together with a package insert in a cardboard pack.

STORAGE

ListB.

Store in a dry place at a temperature of 5 to 30'C.

Keep out of the reach of children!

SHELF-LIFE

3 years.

Do not use the drug after the expiry date indicated on its pack.

DISPENSING TERMS

The drug to be prescribed.

motility - перистальтика; colon – толстая кишка

maternal – материнский; lavage – промывание

№ 3

(итоговый контроль 2 курс)

Phials & 100 coated tablets

Cuprenil®

Available on doctor's prescription,

Composition of each coated tablet: d-Penicillaminum 0,25

SPHERE OF ACTIVITY: Cuprenil forms complexes with metals. It intensifies lead, mercury, and copper ions excretion from the system. It is easily resorbed from the alimentary track and readily excreted with urine. As a mercury complex-forming factor it finds application in treatment of Wilson's syndrom resulting from disturbed copper metabolism in the body. Cuprenil is also advantageously used in treatment of thallium and lead-poisoning and in rheumatoid arthritis.

SIDE EFFECTS: The preparation may develop allergic reactions such as skin effloresce, itching, headache, nausea and ganglia problems. It sometimes leads to iron insufficiency. In such cases it is necessary to reduce the dose or even temporarily withdraw the preparation. Treatment should be restarted with small doses later gradually increased.

DOSAGE: In the absence of specific medical recommendations 3-6 coated tablets are commonly administered daily to adults and children. In more serious cases the daily dose may be increased up to 16 coated tablets daily. Infants over 6 months of age are given 1 tablet daily. During treatment blood check-ups are recommended.

In rheumatic arthritis Cuprenil is administered in gradually increasing doses starting from 0,5-1,75 g daily, given along with vitamins, especially Be and iron.

MANUFACTURER: KUTNO POLAND

№ 4

(итоговый контроль 2 курс)

IBUPROFEN – TEVA

Tablets

Composition: IBUPROFEN – TEVA – 200 mg

Each tablet contains: IBUPROFEN 200 mg

Action: Ibuprofen is a non-steroidal anti-inflammatory agent that possesses analgesic and antipyretic properties. In patients treated with ibuprofen for rheumatoid arthritis and osteoarthritis, the anti-inflammatory action has been shown by reduction in joint swelling, pain and duration of morning stiffness. The use of ibuprofen is not restricted in patients of advanced age. Ibuprofen is readily absorbed and reaches peak plasma levels in approximately 1 hour.

Indications: Ibuprofen is indicated for the treatment of rheumatoid arthritis and osteoarthritis. It is indicated both in treatment of acute flares and in the long-term management of these diseases. Ibuprofen is indicated for the relief of mild to moderate pain and for the treatment of primary dysmenorrhea.

Contraindications: Ibuprofen should not be used in patients who have previously exhibited hypersensitivity, or in individuals with the syndrome of nasal polyps, angioedema, bronchospastic reactivity to aspirin or other non-steroidal anti-inflammatory agents. Anaphylactoid reactions have occurred in such patients.

Warnings: Ibuprofen should be given under close supervision with the history of upper gastrointestinal tract disease

Use in Pregnancy: Administration of Ibuprofen is not recommended during pregnancy.

Use in Breastfeeding: Safety of use in breastfeeding has not been established, ibuprofen is not recommended for use in nursing mothers.

Adverse reactions: Gastrointestinal: Epigastric pain, heartburn, abdominal distress, nausea and vomiting, indigestion, constipation, abdominal

cramps or pain, fullness of gastrointestinal tract.

Central Nervous System: Dizziness, headache, nervousness, convulsions, pain in the spinal column.

Dermatological: Rash (including maculopapular type), pruritis.

Special Senses: Tinnitus.

Metabolic/ Endocrine: Decreased appetite.

Cardiovascular: Edema, fluid retention.

Hematological: Neutropenia, agranulocytosis, aplastic anemia, thrombocytopenia, decreased hemoglobin.

Allergic: Fever.

Other: Stiffness.

Dosage and Administration: The total daily dose of Ibuprofen should not exceed 3200 mg. If gastrointestinal complains occur, administer Ibuprofen with meals or milk. Rheumatoid Arthritis and Osteoarthritis: 1200-2400 mg daily. The dosage should be tailored to each patient, and may be lowered or raised depending on the severity of symptoms either at time of initiating drug therapy or as the patient responds or falls to respond.

Mild to Moderate pain: 400 mg every 4-6 hours as necessary for the

relief of pain.

Primary Dysmenorrhea: 400 mg every 4 hours as necessary, beginning with the earliest onset of pain.

Overdosage: Manifistations: Drowsiness, heartburn, nausea, vomiting, dizziness, nystagmus, apnea, or cyanosis.

Treatment: Employ usual supportive measures. Empty the stomach by inducing vomiting or by gastric lavage, followed by administration of activated charcoal.

№ 5

(итоговый контроль 2 курс)

CARCIL

Composition: One coated tablet contains: active ingredient: 0.035g Silymarinum

Pharmacological action: Carsil is a pharmaceutical of plant origin. It strengthens cell membranes and improves metabolism, stimulates protein synthesis in hepatic cells. Improves the disturbed hepatic function and the general condition of the patient, enhances the appetite it protects the hepatic cells from toxic effect and from accumulation of lipids in them. Carsil is non-toxic and is assimilated very well by the body.

Indications: Itis administered as a single therapeutic agent or as an adjuvant in the therapy of acute and chronic hepatitis, cirrhosis of the liver and fatty degeneration of liver (steatosis), some inborn diseases in bilirubin metabolism. It is prophylactically used in drug, toxic and radiation impairment of the liver.

Contraindications: Hypersensitivity to some of the drug ingredients.

Adverse reactions: The tolerance of the drug is very good when administered in therapeutic doses. Stomach discomfort and mild diarrhea can be observed very rarely.

Drug and other interactions: Carsil should not be used concurrently with alcohol, which has a harmful effect on liver. The drug can be administered simultaneously with agents improving the hepatic function.

Precautions: To obtain the desired therapeutic effect, this drug should be administered strictly according to the prescription of your physician - in the prescribed dose and duration of the therapeutic course.

If during the treatment some of the indicated unfavourable drug reactions or any other manifestations occur, contact immediately your physician.

Pregnancy and breast feeding: The drug can be used during pregnancy and breast feeding period only in compliance with physician's prescription and supervision.

Usage by drivers and machine operators: Carsil can be administered during driving and machine operation.

Administration and dosage: The drug is administered in a dose of 2 tablets, 3 times daily, except otherwise recommended by your physician. The daily dose can be increased in accordance to physician's opinion. It is usually administered prophylactically in a dose of 1 tablet, 3 times daily. The therapeutic course should not be shorter than 3 months.

The daily dose and duration of treatment of children is prescribed by the physician.The tablets are taken with a little liquid during meals, not chewed.

Overdosage: Overdosage is likely to occur when a drug is administered in a dose higher than that prescribed by the physician. Carsil is practically non-toxic and no overdosage has so far been reported.

Supplied: Packages of 80 coated tablets of 35 mg. Packages of 500 coated tablets of 35 mg.

Storage: In a dry. humidity-protected place at temperature of 15° - 25° C.

Exp. term: 3 (three) years after manufacturing date.

Do not use Carsil after the exp. term indicated on the package!

№ 6 Экзаменационная аннотация на лекарственный препарат для перевода без словаря по дисциплине «Английский язык» (итоговый контроль 2 курс) Vitacic ® Eye drops

THIS MEDICINAL PRODUCT IS RECOMMENDED FOR USE IN THE FOLLOWING CASES: THERAPEUTIC INDICATIONS: Vitacic ® is an ophthalmic solution containing an original combination of 5 nucleosides and nucleotide which promotes the complete healing of the cornea in syndromes where epithelial continuity is disrupted. Vitacic ® is intended to be used in the treatment of loss of corneal substance: keratitis, after-effects of keratoplasty, corneal wounds, corneal burns, traumatic ulcers.

WARNING! THIS MEDICINAL PRODUCT SHOULD NOT BE USED IN THE FOLLOWING CASES:

(CONTRA-INDICATIONS)

• history of allergy to one of the ingredients.

IF IN DOUBT, ASK YOUR DOCTOR OR PHARMACIST FOR ADVICE. SPECIAL WARNINGS

Do not inject or swallow.

PRECAUTIONS FOR USE

Use this medicinal product WITH CARE:

• In the event of hypersensitivity, stop the treatment.

• In case of a concomitant treatment with another ophthalmic solution, wait 15 minutes between each instillation.

• Do not touch the eye with the tip of the bottle.

• After use, close the bottle tightly.

PREGNANCY AND LACTATION

As a general rule, it is recommended to ask your doctor or pharmacist for advice before using this medicine, if you are pregnant or nursing mother. ABILITY TO DRIVE AND OPERATE MACHINERY

Patients with blurred vision should refrain from driving a vehicle or operating machinery. INSTRUCTIONS FOR USE AND DOSAGE

1 or 2 drops, 3 to 6 times daily.

METHOD AND ROUTE OF ADMINISTRATION

Certain precautions should be taken to ensure the proper use of the eye drops:

• wash your hands carefully before performing the instillation.

• screw in the perforating cap completely in order to make a hole through

the tip of the bottle.

• unscrew the cap.

• instill one drop - by holding the bottle in a vertical upside-down position

and by pressing the container with the thumb and the forefinger - into the

lower conjunctival sac of the eye to be treated while looking upwards and

gently pulling the lower lid downwards.

• avoid contact between the applicator tip and the eye and eyelids.

• after use, close the bottle again.

DURATION OF TREATMENT

Follow your doctor's prescription.

UNDESIRABLE AND ADVERSE REACTIONS (ADVERSE EFFECTS)

Local intolerance reactions (transient irritation and allergic reactions may

occur).

INFORM YOUR DOCTOR OR PHARMACIST OF ANY UNDESIRABLE OR

ADVERSE REACTIONS NOT MENTIONED ABOVE.

STORAGE

Do not use after the expiry date which is clearly indicated on the package.

continuity - целостность to discrupt - нарушать to blur – расплываться; затуманиваться lid - веко sac – мешок, мешочек; сумка