: ; ; - .
: - . - .
: , 3/;; , , ; ; , ; , ; ; , × 2/3; , ; , ; , 3/; , ; , ×/; s ; , ; , ; t , ; , 3; u , 3; i - , 3; , 3; , 3; b , , 3; D , 3; , , ×; e ; r , / . ; , ; , ; , -1; : i i - .
- [1], - ().
, : LH (Left Heart);
SC (Systemic Circulation); RH (Right Heart); PC (Pulmonary Circulation) (. 1). . , [2].
CCC i - (. 2) , , : qi (t), Vi (t), Pi (t),
i .
Vi (t) i- qi 1(t) qi (t). [2]:
(1)
(2)
. 1.
(3)
(4)
. , . [2]:
|
|
(5)
(6)
(7)
(8)
Ri, , . , . , , . () D i , , [3]:
(9)
, qi .
. .
[5],
(10)
,
(11)
,
(12) (12)
Pi (t) i Vi (t) [3, 4]:
(13)
(14)
U SC, U PC , ( ).
Pi (t) Vi (t) i . , .
, (. 3, ) [4, 5]:
(15)
(16)
(15) (16) :
. (17)
. 3. ():
;
;
.
(. 3, ). () ().
CE, , SE PE. , VE.
. 3, .
PE , .
[5]:
(18)
SE,PE i - [5]:
|
|
(19)
(20)
(17) (20) , i -
.
(21)
, , Vi (t) i (t)
(22)
(23)
; () ; , () [4],
(24)
(25)
; , ,
(21) (22) (25)
, (26)
. (27)
, (21), (26), (27)
[5]:
. (28)
(28) (. 3, ).
= + = (23), (25)
(29)
(28) t (19), (29) :
, .
(30)
, (21), (26), (27), (30) .
[4]:
, . (31)
, , [5]. [4],
(32)
(31) ,
(33)
(33) (31).
(32), (33) ,
(34)
(34)
(35)
(36)
, (21), (26), (27), (33), (35), (36) .
, () (). : T T sys. . T T sys , t es(n) t ed(n) n- , n = 1, 2, 3, , :
(37)
(31) (33), (30).
.
, (1) (14), (21), (26), (27), (30), (33), (35) (37) , , i - , .
++.
4 [2].
q, 3/
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0 1 2 t,
. 4. LH, SC, RH, PC
. , .
. , on-line. [1]. - . , , .
- , .
- . , .
1. / .. [ .]. : , 2011 248 .
2. - , 2008 / .. [ .] // . . . . -. 2008. . 14, 4. . 892902.
3. , . / .. // . . 2005. 4. . 1424.
4. , .. / .. . .: , 1991. 256 .
5. , .. / .. , .. // . . 2006. 1. . 1621.