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020200.62
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1.
1. - - - -
2. - - - -
3. - - -
4. - - - -
2.
1.
2.
3.
4.
3. ,
1.
2.
3.
4.
4. ,
1. 1940
2. 1944
3. 1953
4. 1957
5. ,
1. 1940
2. 1944
3. 1953
4. 1957
6.
1. E.coli
2. S.cerevisae
3. B.subtilis
7.
1. S.cerevisae
2. B.subtilis
3. E.coli
8.
1.
2.
3.
4.
5. SV-40
9.
1.
2.
3.
4.
10.
1. SV-40
2.
3.
4.
5.
11.
1. SV-40
2.
3.
4.
12.
1. SV-40
2.
3.
13.
1.
2.
3.
4.
14. ,
1.
2.
3.
4.
15. ,
1.
2.
3.
4.
16.
1.
2.
3.
17.
1.
2.
3.
4.
18. ,
1. 200 - 250
2. 270 - 300
3. 320 - 370
4. 1000
19.
1.
2.
3.
20.
1.
2.
21.
1. 30 -
2. 40 -
3. 1971
22.
1.
2. -
3.
23.
1. 1968
2. 1971
3. 1973
4. 1977
24.
1. 1
2. 1
3. 2
4. 2
25.
1.
2.
26.
1.
2.
27.
1.
2.
3.
4.
28.
1.
2.
3.
4.
29. -
1.
2. -
3. -
4.
30. -
1. -
2. -
3. -
31.
1. -
2. -
3. -
|
|
32. , 2
1.
2.
3.
33. , 2
1.
2.
3.
34. , 2
1.
2.
3.
4.
35.
1.
2.
3.
4.
36.
1.
2.
3.
37.
1.
2.
3.
4.
38. ()
1. 37
2. 65
3. 100
39. ()
1. 37
2. 65
3. 100
40.
1.
2.
3. -
41.
1. -
2. -
3. -
4.
42. -
1.
2.
3.
43. , , , ,
1.
2.
3.
4.
44.
1. 1971
2. 1972
3. 1973
4. 1974
45.
1.
2. 2-
3. ,
4. ,
46.
1.
2.
3.
47. ,
1.
2.
3.
48.
1. 1
2. 2
3. 3
4. 4
49.
1. 5-3 3-5
2. 5-3 3-5
3. 5-3 5-3
4. 3-5 5-3
50.
1. 5-3
2. 3-5
3. 5-3
4. 3-5
51.
1. 5-3
2. 3-5
3. 5-3
4. 3-5
52.
1. 5-3
2. 3-5
3. 5-3
4. 3-5
53. , 10 ..,
1. 5-3
2. 3-5
3. 5-3
4. 3-5
54.
1. 5 -
2. 3
55.
1. 1
2. 2
3. 3
4. 1 3
5. 2 3
56.
1. 1
2. 2
3. 3
4. 1 3
5. 2 3
57. 1
1. 1 3
2. 2 3
3. 1 2
4. 2
5. 3
58.
1. 1 3
2. 2 3
3. 1 2
4. 2
5. 3
|
|
59.
1. Hpa I Eco RI
2. Hind III Eco RI
3. Hpa I Hind III
60.
1.
2.
3.
61.
1.
2.
3.
62.
1. 1 , 2
2. 1 1 2
3. 1 , 2
63.
1.
2. pBR 322
3.
4. SV-40
64.
1.
2.
3.
4.
65.
1.
2. 1
3. 4
66.
1.
2.
3.
67.
1.
2.
3.
4.
68.
1.
2.
3.
69.
1. 3-
2. 5-
3. 3- 5-
70.
1.
2.
3.
71.
1.
2.
72.
1.
2.
3. 1
4. 3
73. ()
1. 65
2. 70
3. 80
4. 100
74.
1.
2.
3.
4.
75.
1.
2.
3.
76.
1.
2.
3.
77.
1.
2.
3.
78.
1.
2.
3.
79.
1.
2.
80.
1.
2.
81.
1.
2.
82.
1. in vitro
2. in vivo
83.
1. in vitro
2. in vivo
84.
1. in vitro
2. in vivo
85.
1.
2.
86.
1. 1973
2. 1976
3. 1977
4. 1985
87.
1.
2.
3.
4.
88.
1.
2.
3.
4.
89.
1.
2.
3.
90. in vitro ( )
1. 5
2. 10
3. 15
4. 20
91.
1.
2.
3.
92. b-
1.
2.
3.
4.
93. , l
1.
2.
3.
4.
94. , l
1.
2.
3.
95.
1.
2.
3.
4.
96.
1.
2. -
3.
|
|
97.
1.
2.
3.
98.
1.
2.
99.
1.
2.
100.
1.
2.
101. 1
1. 10
2. 100
3. 1000
102.
1.
2.
3.
103.
1.
2.
3.
104. (%)
1. 1
2. 10
3. 30
4. 50
5. 100
105.
1. Pol I
2. Pol II
3. Pol III
106.
1. Pol I
2. Pol II
3. Pol III
107. ,
1. Pol I
2. Pol II
3. Pol III
108.
1.
2.
3.
109.
1. 1 2
2.
3. 1-
4. 2-
110.
1.
2.
3.
111.
1.
2.
3.
112.
1.
2.
113. ,
1. -
2.
3.
114. -
1.
2.
115.
1.
2.
3.
116. 180
1.
2.
:
117. _____________.
118. , _______.
119. _________
120. __________
121. , - _________
122. - ______________
123. , ___________.
124. , , ___________
125. , , - _______
126. 6-8 , - __________ _____________.
127. ____________.
128. , - ________
129. , Streptomyces albus, _____
130. , Escherichia coli, _____
131. , Streptcoccus aureus, _____
132. , Streptomyces albus, _____
133. , Escherichia coli, _____
134. , Streptcoccus aureus, _____
135. , Haemophilus parahaemolyticus, _____
136. __________ ________
137. , - _______________.
138. - ____________.
139. , , _____________.
140. - , - __________.
141. in vitro ________________ ____________.
142. _______ ________.
143. ______________.
144. - ___________.
145. ____________.
146. , - ________.
147. , - _____________.
148. , - ____________.
149. , - ______________.
150. , - ____________.
151. __________ ____________.
152. , Bacillus subtilis, _____
153. , - ____________
154. , - _______________.
155. , ___________.
156. , - ____________
157. , , - _____________.
158. . - - _______________.
159. ,
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1, 17, 29, 48, 134,80,127 | 2, 18, 31,49, 133,81,128 | 3, 19, 32,50, 132,82,129 | 4, 20, 33,51, 131,83,130 | 5, 21, 34,52, 130,84,131 | 6, 22, 35,53, 129,85,132 | 7, 23, 36,54, 128,86,133 | 8, 24, 37,55, 127,88,134 | 9, 25, 38,56, 126,89,135 | 10, 26, 30,57, 125,87,136 | |
11, 27, 40,52, 124,90,137 | 12, 28, 29,46, 123,91,138 | 13, 17, 31,45, 122,92,139 | 14, 18, 33,44, 121,93,140 | 15, 19, 40,43, 120,94,141 | 16, 20, 34,42, 119,95,142 | 1, 21, 39,41, 118,96,143 | 2, 22, 40,60, 117,97,144 | 3, 23, 30,59, 116,98,145 | 4, 24, 40,58, 115,99,146 | |
5, 25, 36,45, 114,70,147 | 6, 19, 26, 32, 113,71,148 | 7, 27, 29,51, 112,72,149 | 8, 28, 31,44, 111,73,150 | 9, 17, 37,58, 110,74,151 | 10, 18, 39,60, 109,75,152 | 11, 19, 34, 42, 108,76,153 | 12, 20, 30,50, 107,77,154 | 13, 21, 37,56, 106,78,155 | 14, 22, 38, 47, 105,79,156 | |
15, 23, 32,59, 135,43,157 | 16, 24, 38,49, 103,85,158 | 1, 25, 38,51, 102,72,159 | 2, 26, 58, 39, 101, 126,85 | 3, 27, 31,52, 100,94,127 | 4, 28, 37,44, 99,112,128 | 5, 17, 30, 56, 98,130,129 | 6, 18, 34, 55, 97,69,130 | 7, 19, 39,60, 96,123,131 | 8, 20, 33, 44, 95,110,132 | |
9, 21, 39,47, 94,127,133 | 10, 22, 40,51, 93,128,134 | 11, 23, 39, 47, 92,129,135 | 12, 25, 33, 44, 91,130,136 | 13, 26, 31,59, 90,131,137 | 14, 28, 30,58, 89,132,138 | 15, 27, 31,42, 88,133,139 | 16, 28, 36,45, 87,134,140 | 1, 17, 34, 56, 86,102,141 | 2, 18, 39,57, 85,103,142 | |
3, 19, 38,51, 84,104,143 | 4, 21, 38,53, 83,105,144 | 5, 20, 33,50, 82,106,145 | 6, 23, 29,57, 81,107,146 | 7, 22, 30,59, 80,108,147 | 8, 25, 29,60, 79,109,148 | 9, 24, 38,49, 78,110,149 | 10, 27, 31,54, 77,111,150 | 11, 25, 39,42, 76,112,151 | 12, 24, 34,52, 75,113,152 | |
13, 17, 32,41, 74,114,153 | 14, 18, 33,42, 73,115,154 | 15, 19, 40,59, 72,116,155 | 16, 20, 30,43, 71,117,156 | 1, 21, 30,44, 70,118,157 | 2, 22, 31,45, 69,119,158 | 3, 23, 29,46, 68,120,159 | 4, 24, 39,47, 67,121,127 | 5, 26, 31,60, 113,95,128 | 6, 27, 40,55, 66,122,129 | |
7, 28, 33,48, 65,123,130 | 8, 28, 32,49, 64,124,131 | 9, 17, 30,50, 73,125,132 | 10, 18, 38,51, 100,78,133 | 11, 19, 39,52, 101,77,134 | 12, 20, 32,52, 102,83,135 | 13, 21, 34,53, 103,84,136 | 14, 22, 29,54, 104,85,137 | 15, 28, 33,52, 105, 86,138 | 16, 23, 31,45, 106,87,139 | |
1, 27, 34, 55, 107,72,140 | 2, 26, 30,56, 108,74,141 | 3, 22, 40,57, 109,75,142 | 4, 25, 39,58, 110,76,143 | 5, 26, 40,59, 111,77,144 | 6, 17, 33,60, 112, 78,145 | 7, 18, 38,45, 113,79,146 | 8, 19, 35, 41, 114,90,147 | 9, 20,29,53, 115,134, | 10,21,38,56,116, 133, ,149 | |
11,22,30,42,,150 117,132 | 12, 23, 37,43, 153 118,131 | 13, 24, 32,44,,154 119,57 | 14, 27, 40,68,,155 120,93 | 15, 23, 38,66,,156 121,84 | 16, 23, 30,51,,157 122, 74 | 1, 22, 40,78,,158 123, 59 | 2, 17, 39,99,,159 124,55 | 3, 18, 33,41,160 125,96 | 4, 19, 29,45,143 126,87 |