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020200.62

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, . . ,

 

 

- _____________________2013 ., _____.

 

 

, . . ,


1. .. 4

2. 5

3. ... 6

4. .. 6

5. ......21

6. ҅...22


1.

, . , , . , , .

, , , .

, . .


 

 

.

:

1. ;

2. ;

3. ;

4. ;

.

, , ( , , ..).

. . . . . . .

- () . () . . , . . "" . " ". . . .

. . - , . - . . . . ( ) .

. . . ( ). .

, . . . " . E.coli R1 . .

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. ; , . . .

. ( ) . , .

: , , . . , .

 

  1. .
  2. .
  3. ?
  4. " ".
  5. .
  6. .
  7. ?
  8. ?

:


1.
1. - - - -
2. - - - -
3. - - -
4. - - - -


2.
1.
2.
3.
4.


3. ,
1.
2.
3.
4.


4. ,
1. 1940
2. 1944
3. 1953
4. 1957


5. ,
1. 1940
2. 1944
3. 1953
4. 1957


6.
1. E.coli
2. S.cerevisae
3. B.subtilis


7.
1. S.cerevisae
2. B.subtilis
3. E.coli


8.
1.
2.
3.
4.
5. SV-40


9.
1.
2.
3.
4.


10.
1. SV-40
2.
3.
4.
5.


11.
1. SV-40
2.
3.
4.

 

 


12.
1. SV-40
2.
3.


13.
1.
2.
3.
4.


14. ,
1.
2.
3.
4.


15. ,
1.
2.
3.
4.


16.
1.
2.
3.


17.
1.
2.
3.
4.


18. ,
1. 200 - 250
2. 270 - 300
3. 320 - 370
4. 1000


19.
1.
2.
3.


20.
1.
2.

 

 


21.
1. 30 -
2. 40 -
3. 1971


22.
1.
2. -
3.


23.
1. 1968
2. 1971
3. 1973
4. 1977


24.
1. 1
2. 1
3. 2
4. 2


25.
1.
2.


26.
1.
2.


27.
1.
2.
3.
4.


28.
1.
2.
3.
4.


29. -
1.
2. -
3. -
4.

 


30. -
1. -
2. -
3. -


31.
1. -
2. -
3. -


32. , 2
1.
2.
3.


33. , 2
1.
2.
3.


34. , 2
1.
2.
3.
4.


35.
1.
2.
3.
4.


36.
1.
2.
3.


37.
1.
2.
3.
4.


38. ()
1. 37
2. 65
3. 100


39. ()
1. 37
2. 65
3. 100


40.
1.
2.
3. -


41.
1. -
2. -
3. -
4.


42. -
1.
2.
3.


43. , , , ,
1.
2.
3.
4.


44.
1. 1971
2. 1972
3. 1973
4. 1974


45.
1.
2. 2-
3. ,
4. ,


46.
1.
2.
3.


47. ,
1.
2.
3.


48.
1. 1
2. 2
3. 3
4. 4


49.
1. 5-3 3-5
2. 5-3 3-5
3. 5-3 5-3
4. 3-5 5-3


50.
1. 5-3
2. 3-5
3. 5-3
4. 3-5


51.
1. 5-3
2. 3-5
3. 5-3
4. 3-5


52.
1. 5-3
2. 3-5
3. 5-3
4. 3-5


53. , 10 ..,
1. 5-3
2. 3-5
3. 5-3
4. 3-5


54.
1. 5 -
2. 3


55.
1. 1
2. 2
3. 3
4. 1 3
5. 2 3

 


56.
1. 1
2. 2
3. 3
4. 1 3
5. 2 3


57. 1
1. 1 3
2. 2 3
3. 1 2
4. 2
5. 3


58.
1. 1 3
2. 2 3
3. 1 2
4. 2
5. 3


59.
1. Hpa I Eco RI
2. Hind III Eco RI
3. Hpa I Hind III


60.
1.
2.
3.


61.
1.
2.
3.


62.
1. 1 , 2
2. 1 1 2
3. 1 , 2


63.
1.
2. pBR 322
3.
4. SV-40


64.
1.
2.
3.
4.

 

65.
1.
2. 1
3. 4


66.
1.
2.
3.


67.
1.
2.
3.
4.


68.
1.
2.
3.


69.
1. 3-
2. 5-
3. 3- 5-


70.
1.
2.
3.


71.
1.
2.

 

72.
1.
2.
3. 1
4. 3


73. ()
1. 65
2. 70
3. 80
4. 100


74.
1.
2.
3.
4.


75.
1.
2.
3.


76.
1.
2.
3.


77.
1.
2.
3.


78.
1.
2.
3.


79.
1.
2.


80.
1.
2.


81.
1.
2.


82.
1. in vitro
2. in vivo


83.
1. in vitro
2. in vivo


84.
1. in vitro
2. in vivo

 


85.
1.
2.


86.
1. 1973
2. 1976
3. 1977
4. 1985


87.
1.
2.
3.
4.


88.
1.
2.
3.
4.


89.
1.
2.
3.


90. in vitro ( )
1. 5
2. 10
3. 15
4. 20


91.
1.
2.
3.


92. b-
1.
2.
3.
4.


93. , l
1.
2.
3.
4.

94. , l
1.
2.
3.


95.
1.
2.
3.
4.


96.
1.
2. -
3.


97.
1.
2.
3.


98.
1.
2.


99.
1.
2.


100.
1.
2.


101. 1
1. 10
2. 100
3. 1000


102.
1.
2.
3.


103.
1.
2.
3.


104. (%)
1. 1
2. 10
3. 30
4. 50
5. 100


105.
1. Pol I
2. Pol II
3. Pol III


106.
1. Pol I
2. Pol II
3. Pol III


107. ,
1. Pol I
2. Pol II
3. Pol III


108.
1.
2.
3.


109.
1. 1 2
2.
3. 1-
4. 2-


110.
1.
2.
3.


111.
1.
2.
3.


112.
1.
2.


113. ,
1. -
2.
3.

 

 

114. -
1.
2.


115.
1.
2.
3.


116. 180
1.
2.

:

117. _____________.
118. , _______.
119. _________
120. __________
121. , - _________
122. - ______________
123. , ___________.
124. , , ___________
125. , , - _______
126. 6-8 , - __________ _____________.
127. ____________.
128. , - ________
129. , Streptomyces albus, _____
130. , Escherichia coli, _____
131. , Streptcoccus aureus, _____
132. , Streptomyces albus, _____
133. , Escherichia coli, _____
134. , Streptcoccus aureus, _____
135. , Haemophilus parahaemolyticus, _____
136. __________ ________
137. , - _______________.
138. - ____________.
139. , , _____________.
140. - , - __________.
141. in vitro ________________ ____________.
142. _______ ________.
143. ______________.
144. - ___________.
145. ____________.
146. , - ________.
147. , - _____________.
148. , - ____________.
149. , - ______________.
150. , - ____________.
151. __________ ____________.
152. , Bacillus subtilis, _____
153. , - ____________
154. , - _______________.
155. , ___________.
156. , - ____________
157. , , - _____________.
158. . - - _______________.
159. ,


\ , ( .)  
 
:  
1. : . . , . . , . . .:    
2. .. :    
3. . . .. ..    
4. .. .:    
  ..    
  : . , . . .:    
  : / . . . . , . .:    
  , . .1,2 , . . . -    
  . . .., .. 2009.  
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:  
  .. .:    
  . 2 .   . . , . , . . .:    
  . . .. .:    
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  . . .   .., ..    
  .., ., . . .:    
  .   .., .. .: -    
             

-
                   
  1, 17, 29, 48, 134,80,127 2, 18, 31,49, 133,81,128 3, 19, 32,50, 132,82,129 4, 20, 33,51, 131,83,130 5, 21, 34,52, 130,84,131 6, 22, 35,53, 129,85,132 7, 23, 36,54, 128,86,133 8, 24, 37,55, 127,88,134 9, 25, 38,56, 126,89,135 10, 26, 30,57, 125,87,136
  11, 27, 40,52, 124,90,137 12, 28, 29,46, 123,91,138 13, 17, 31,45, 122,92,139 14, 18, 33,44, 121,93,140 15, 19, 40,43, 120,94,141 16, 20, 34,42, 119,95,142 1, 21, 39,41, 118,96,143 2, 22, 40,60, 117,97,144 3, 23, 30,59, 116,98,145 4, 24, 40,58, 115,99,146
  5, 25, 36,45, 114,70,147 6, 19, 26, 32, 113,71,148 7, 27, 29,51, 112,72,149 8, 28, 31,44, 111,73,150 9, 17, 37,58, 110,74,151 10, 18, 39,60, 109,75,152 11, 19, 34, 42, 108,76,153 12, 20, 30,50, 107,77,154 13, 21, 37,56, 106,78,155 14, 22, 38, 47, 105,79,156
  15, 23, 32,59, 135,43,157 16, 24, 38,49, 103,85,158 1, 25, 38,51, 102,72,159 2, 26, 58, 39, 101, 126,85 3, 27, 31,52, 100,94,127 4, 28, 37,44, 99,112,128 5, 17, 30, 56, 98,130,129 6, 18, 34, 55, 97,69,130 7, 19, 39,60, 96,123,131 8, 20, 33, 44, 95,110,132
  9, 21, 39,47, 94,127,133 10, 22, 40,51, 93,128,134 11, 23, 39, 47, 92,129,135 12, 25, 33, 44, 91,130,136 13, 26, 31,59, 90,131,137 14, 28, 30,58, 89,132,138 15, 27, 31,42, 88,133,139 16, 28, 36,45, 87,134,140 1, 17, 34, 56, 86,102,141 2, 18, 39,57, 85,103,142
  3, 19, 38,51, 84,104,143 4, 21, 38,53, 83,105,144 5, 20, 33,50, 82,106,145 6, 23, 29,57, 81,107,146 7, 22, 30,59, 80,108,147 8, 25, 29,60, 79,109,148 9, 24, 38,49, 78,110,149 10, 27, 31,54, 77,111,150 11, 25, 39,42, 76,112,151 12, 24, 34,52, 75,113,152
  13, 17, 32,41, 74,114,153 14, 18, 33,42, 73,115,154 15, 19, 40,59, 72,116,155 16, 20, 30,43, 71,117,156 1, 21, 30,44, 70,118,157 2, 22, 31,45, 69,119,158 3, 23, 29,46, 68,120,159 4, 24, 39,47, 67,121,127 5, 26, 31,60, 113,95,128 6, 27, 40,55, 66,122,129
  7, 28, 33,48, 65,123,130 8, 28, 32,49, 64,124,131 9, 17, 30,50, 73,125,132 10, 18, 38,51, 100,78,133 11, 19, 39,52, 101,77,134 12, 20, 32,52, 102,83,135 13, 21, 34,53, 103,84,136 14, 22, 29,54, 104,85,137 15, 28, 33,52, 105, 86,138 16, 23, 31,45, 106,87,139
  1, 27, 34, 55, 107,72,140 2, 26, 30,56, 108,74,141 3, 22, 40,57, 109,75,142 4, 25, 39,58, 110,76,143 5, 26, 40,59, 111,77,144 6, 17, 33,60, 112, 78,145 7, 18, 38,45, 113,79,146 8, 19, 35, 41, 114,90,147 9, 20,29,53, 115,134, 10,21,38,56,116, 133, ,149
  11,22,30,42,,150 117,132 12, 23, 37,43, 153 118,131 13, 24, 32,44,,154 119,57 14, 27, 40,68,,155 120,93 15, 23, 38,66,,156 121,84 16, 23, 30,51,,157 122, 74 1, 22, 40,78,,158 123, 59 2, 17, 39,99,,159 124,55 3, 18, 33,41,160 125,96 4, 19, 29,45,143 126,87

 



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