- - ( ), (- ), . (d---) .
/ / - , ( , ).
- , , , .
- , . . . , . , .
/ - , ,
; .
/ / - ; .
/ - (, ). . , .
/ - , , . , .
- , , , , , .
- /:
, -.
- / .
/ / FDA / - :
EFA - Caps (Allerderm/Virbac); (OTC); : 50 , - 25 , - 10 , 11 ME 850 ME.
|
|
|
EFA - Caps HP (Allerderm/Virbac); (OTC): 100 , - 60 , - 30 , 11 ME 850 ME.
EFA Liquid (Allerderm/Virbac); (OTC); : 1,8 /, 230 /, -
FEBANTEL 319
D2 54 / , -, , , , . .
Dermcaps , Dermcaps ES Dermcaps ES Liquid (DVM); (): , .
:
, .
FEBANTEL -
- - - , . . -. in vivo - , .
/ / - .
- (Rintal ) 1 . (Combot ) 2 . . .
- , , . , -.
/ - ( ) { Strongulus vul - garis, S. edentatus, S. equinus), (. equorum - ) (Oxyuris equi - 4 ) . { Combotel ) , -
(Gastrophilus intestinalis, G. nasalis).
( - Vercom ) : (Ancylostoma caninum), { Toxocara canis) (Dipytidium caninum Taenia pisiformis) { Trichuris vulpus).
( - Vercom ) : { Ancylostoma tubaeforme), { Toxocara canti) (Dipylidium caninum Taenia taeniae - formis) .
, 85% : , , , { Oesophogo - stomum spp.), , { F. hepatica - 4 15- ; ).
|
|
|
- -, . . , . 6-12 , - 12-24 .
/ - - . , - . { Combotel ) , , , .
{ Vercom ) .
/ - . , . ( 8 ).
FEBANTEL
Combotel : , . .
Vercom ( ) . , , , . 3%. , , . .
/ - , ' 40. 3 , -. 8 .
, - (Combotel ). , , . .
LD50 10 /. , , 15 , - 10 . , 5 10 / per os 90 , .
/ - .
- :
- Vercom (. ): ) 6 : 10 / ()/ 1 / () per os 3 ; : 15 / ()/ 1,5 / () per os 3 ( Vercom Paste - Miles).
|
:
- Vercom (. ): ) 6 : 10 / ()/
1 / () per os 3 ;
: 15 / ()/ 1,5 / () per os 3 ( Vercom Paste - Miles).
|
|
|
:
, :
) 5-10 / per os (Blagburn et al. 1989);
) 10 / per os (Roberson 1988b).
:
: ) 6 / per os ; , 6-8 (Robinson 1987), ( Rintal Paste & Suspension - Miles).
1) ; 2) , .
- . , Dipylidium - inum, , , .
/ / FDA - :
, 45,5%, 6 36 ;
Rintal Paste (Bayer), (OTC). . , 93 / (9,3%) 26 ;
Rintal Suspension (Bayer); (Rx). .
3,4% (34 /) 0,34% (3,4 /) ; 4,8 , 12 36 ;
Vercom Paste (Bayer), (Rx). , , .
/ -; Drontal Plus Tablets (Bayer) (Rx) , .
Amatron Bayverm .
: .
FENBENDAZOLE 321
FENBENDAZOLE-
- - - ; .
/ / - .
/ - : (Toxocara cams, T. leonina), - (Ancylostoma caninum, Uncinaria stenocephala), (Trichuris vulpis) (Taenia pisiformis). Dipylidium caninum. , Capillaria aerophilia, Filaroides hirthi Paragonimus kellicoti.
: - Haemonchus contortus, Ostertagia ostertagi, Trichostrongylns axei, Bunostomum phleboto - mum, Nematodirus helvetianus, Cooperia spp., Tri chostrongylns colubriformis, Oesophagostomum radia - tum Dictyocaulus vivaparus. , . Moniezia spp. Ostertagia ostertagi 4 , .
: (5. edentatus, S. equinus, S. vulgaris), (Cyathostomum spp., Cylicocylus spp., Cylicostephanus spp., Triodontaphorus spp.) (Oxyuris equi).
: Ascaris suum, Meta - strongylus apri, Oesphagostomum dentatum, . quadrispinulatum, , Hyostrongylus rubidus, Trichuris suis Stephanuris dentatus ( ).
|
|
|
, , , . . .
, .
- -
. 0,11 / 0,07 / . () . , 44-50% 1% - .
/ - , .
/ - , , . , . , , .
( ) ; 3 .
/ - , , 100 . LD50 10 / . .
- - (- , ). .
- :
, , , ( Taenia spp.):
) 50 / per os 3 (
Panacur-Hoechst), (Cornelius and Rober-
son 1986).
) 55 / per os (5
Taenia) (Chiapella 1988), (Reinemeyer 1985).
Ascarids:
a) 50 / per os 1 3 (Todd, Paul, and DiPietro 1985). Capillaria plica:
FENBENDAZOLE
) 50 / 1 3 ;
3 50 /
(Todd, Paul, and DiPietro 1985);
) 50 / per os 3-10
(Brown and Prestwood 1986).
For Capillaria aemphilia:
) 25-50 / 12 10-14
(Hawkins, Ettinger, and Suter 1989);
) 50 / per os 1 10-14
(Reinemeyer 1995).
For Filaroides hirthi:
) 50 / per os 1 14 .
, ,
(Hawkins, Ettinger, and Suter
1989);
) 50 / per os 1 10-14
(Reinemeyer 1995).
- nia spp. ( Dipylidium caninum): ) 50 / per os 3 (Todd, Paul, and
DiPietro 1985).
Paragonimus keUicoti:
) 50-100 / per os,
2 , 10-14 (Todd, Paul, and
DiPietro 1985);
) 50 / per os 1 10-14
(Reinemeyer 1995).
Trichuris Colitis; Typhlitis: ) 50 / per os 1 3 ,
2-3 ,
2 . (DeNovo 1988).
Crenosoma milpis: ) 50 / per os 1 3
(Reinemeyer 1995).
Giardia: ) 50 / per os 1 3
(Barr and Bowman 1994).
Eucoleus boehmi: ) 50 / per os 10-14 ,
(Reinemeyer 1995).
:
, , , ( Taenia spp.): ) 50 / per os 5 (Dimski 1989).
, (Aelurostmngylus abstrusus): ) 20 / per os 1 5 , 5 (Todd, Paul, and DiPietro
1985);
) 25-50 / 12 10-14
(Hawkins, Ettinger, and Suter 1989);
) 50 / per os 10 (Pechman
1989);
) 20 / per os 1 5 ,
5 (Reinemeyer 1995).
, { Capillaria aemphilia):
|
|
|
) 50 / per os 10 (Pechman
1989);
) 50 / per os 1 10-14
(Reinemeyer 1995).
Capillaria feliscati:
) 25 / 2 per os 3-10
(Brown and Prestwood 1986);
) 25 / per os 12 10
(Brown and Barsanti 1989).
Paragonimus kellicoti:
) 50 / per os 10
(Pechman 1989);
) 50 / per os 1 10-14
(Reinemeyer 1995).
:
Haemonchus contortus, Oster - tagia ostertagi, Trichostrongylus axei, Bunostomum phlebotomum, Nematodirus helvetianus, Cooperia spp., Trichostrongylus colubriformis, Oesophagostomum ra - diatum Dictyocaulus vivaparus:
) 5 / per os (Paul 1986);
) 7,5 / per os (Roberson 1988b).
Moniezia spp. Ostertagia ostertagi 4 : a) 10 / per os (Paul 1986), (Roberson 1988b). :
, :
) 5 / per os; 10 / 1
5 5. vulgaris (Ro
binson 1987);
) 5 / per os; 10 /
(Roberson 1988b);
) -
: 50 / per os 3 , 10 /
5 (Herd 1987).
:
, :
) 5 / per os; 3 / 3 ;
10 / (Roberson 1988b);
) : 9 / per os (Braun
1995).
:
, :
FENBENDAZOLE 323
a) 5 / per os 3
(Roberson 1988b).
:
, :
) 10-15 / per os (
) (Fowler 1989);
) 5-10 / per os 1-3 . -
(Cheney and Alien 1989).
:
) Ascaris: 10-50 / per os 1 ; 10
.
(
) .
-: 1050 / per os 1 3 .
CapiUaria: 10-50 / per os 1 5 . , (Clubb 1986).
) , :
1050 / per os 1 3-5
; 20-100 / per os; 125
/ 5 (
: 50 / 5 ); 100 /
5 .
(Marshall 1993).
:
, : ) : 50-100 / per os 1 ;
2-3 ;
strongyMdes (Gauvin 1993).
/ / FDA / - :
222 / (22,2%) 0,18 1, 2 , 4 1 ; Panacur Granules 22,2% (Hoechst), (Rx). .
222 / (22,2%); Panacur Granules 22,2% (Hoechst), (OTC). , .
, 100 / (10%); ; Panacur Suspension (Hoechst), (Rx). ( )
. 8 ( ). Safe - Guard Suspension (Hoechst) (OTC). . 8 .
, 100 / (10%); ; Panacur Paste (Hoechst), (OTC). ( ) . 8 ( ). Safe - Guard Paste (Hoechst) (OTC). , , . 8 , .
, 750 /; 25 ; Safe - Guard Sweetlix (Hoechst); (OTC). . 16 .
.
Safe - Guard EZ Scoop Swine Dewormer (Hoechst) (OTC). 1,8% ; .
Safe-Guard 0,96% Scoop Dewormer (Hoechst) (OTC). . , 13 .
.
Safe-Guard Free-choice Cattle Dewormer (Hoechst) (OTC). 0,50% (2,27 /). . .
Safe - Guard 35% Salt Free - choice Cattle Dewor mer (Hoechst) (OTC). 1,9 / . . 13 ; .
, .
Safe-Guard 0,5% Cattle Top Dress (Hoechst) (OTC). 13 ; .
FENPROSTALENE
Safe-Guard 1,96% Scoop Dewormer Mini Pellets (Hoechst) (OTC). . ; 13 .
, 20% (200 /).
Safe-Guard Premix (Hoechst) (OTC). , , . 13 ; . . ( ) 14 .
: .
FENPROSTALENE -
- - , - -. , - -, .
/ / - . 5 , . .
- , F. : , , .
/ - 150 , - .
- - (-linson, Spires, and Bowen 1985). , .
48 .
/ / - , . - (, , ).
/; /, /. .
/ - . .
- . .
- , . .
-
:
150 : ) 1 /. 92%. 5 ( Bovilene -Syntex).
:
) : , . , . 1 /. 1-5 . . : -
