TCR
CD3-
CD4 CD8
ζ-
- .
-, , , 5% . " ", , NK- . -
, (CD44 - ), . - ().
. 18. -
(, , , ), -. : -1, 6, 7, 11, 12, -α, -b, GM-CSF . - -7. -7- -, CD25. CD44+CD25+ , . CD3 , γ, β έ, TCR .
, - CD34, CD38 ( ), CD7, TdT ( - ; , ).
- , -, NK -, . CD44.
- - (CD44-CD25-) . α/β γ/δ. ( ) CD4+ ( 2 ) CD8+ ( 1 ) (CD4+CD8+ - - ). () CD1 (a, b, c), CD95 ( ). . CD28+ ( 60-70% D8+, CD4+ - , ), CD45 ( ).
, , -, .
|
|
1. .
2. , 1 2 , (, ).
3. , 1 CD4, CD8; , 2 CD8, CD4 ( ).
4. : , .
5. 2-5% .
. 19. -
-
- | |
0 | -2, 3,4,5,6, 10,13; -g, -b |
1 | -2, 3, -g, -b |
2 | -3,4,5,6, 10,13 |
reg | 5, 10, -g, -b |
-2,4,5,10, -g, -g |