. , , . .
O
|| COOH
H2N CH2 COOH C H | (
| COOH )
COOH
- .
, , , , .
.
3 (, , ).
, :
SH CH3 CH3 A
| | |
CH2 S S CH2 O
| | + , |
CH2 CH2 CH2
| | - ,- |
CH NH2 CH2 CH2 OH OH
| | |
COOH CH NH2 CH NH2
| |
COOH COOH
SAM (
A )
S CH2 O SH
| + | CH2OH
(CH2)2 (CH2)2 |
(-3) | | + CH NH2
CH NH2 OH OH CH NH2 |
| | COOH
COOH COOH
S-
H2C S CH2 CH2 OH
| | | CH2 SH
-2 CH2 CH NH2 + CH2 |
| | | + CH NH2
CH NH2 COOH CH NH2 |
| | COOH
COOH COOH
(,
Fe).
SH , :
CH2 SH HS CH2 CH2 S S CH2
| | + |
CH NH2 + CH NH2 CH NH2 NH2 CH2
| | - *2 | |
COOH COOH COOH COOH
, :
CH2SH
|
CO NH CHCO NHCH2
| |
(CH2) CHNH2 COOH
|
COOH
()
CH2SH
|
H2NCH CO NH CH2 COOH H2N CH2 COOH
-
CH2 SH CH2 SH
| |
CH NH2 CO NHCH COOH
| |
COOH (CH2)2 CH COOH
|
NH2
COOH
|
(CH2)2
|
CH NH2
|
COOH
SH- .
+ *2
2GSH 2G S S G 2GSH
- 2H -
( )
. , SH- , 2- .
|
|
:
CH2 SH CH2 SO2H CH2 SO2H
| 2 | | |
CH NH2 CH NH2 C = O
| | |
COOH COOH COOH
CH2 SO3H
CH3 SO3 |
| -2 CH NH2
C = O + |
| -2 COOH
COOH SO4
CH2 SO2H CH2SO3H
| |
CH2 NH2 CH2 NH2
.
, . . :
1. ( 1%) 60% . , .
2. ( 95% , ).
CH2 CH COOH
|
NH NH2
2 2
HO
CH2 CH COOH CO CH2 CH COOH
| |
NH NH2 NHCHO NH2
5-
CO CH2 CH COOH
|
NH2 NH2
CO CH2 CH COOH
|
NH2
NH2 3-
OH
COOH COOH COOH
COOH N COOH NH2
N
| OH
-5-
COOH COOH
N N
| |
-5- ---
:
: ,
: ()
:
: