- - ---; , . . N- N--L-.
/ / - (15-30 ). 96 .
; , , . , , . - , , - . , , , , , , .
- , . - , , . 7-9. .
- (-
ACETYLCYSTEINE 17
), , , .
/ - - , , .
- . - , . - .
/ / ( ) . .
. , , .
- - 17 . , .
|
|
|
/ - (, ) , , . , , , . , , .
. , , .
/ - LD50 - 1 / (per os) 700 / (/). , ( , ).
/ - , . , , 3 . , , .
- :
:
) 150 / per os /,
17 50 / 4 (Bailey 1986a);
) 140 / per os / (
5% ), 3-5 70 /
4 (Oehme 1986a);
) 140 / per os, 7 70
/ per os 6 (Grauer and Hjelle
1988).
:
) 50 / 30-60 12 (Kirk 1986).
: :
) 140 / per os / ( 5%
), 3-5 70 / 4
per os / (Reid and Oehme 1989), (Oehme
1986a);
) 150 / per os /, 17
50 / 4 (Bailey 1986a);
) ,
: 10%
, 37 1,4 / (0,7
/ 20% ) per os
8 (Maggio-Price 1988);
) 140 / per os, 7 70
/ per os 6 (Grauer and Hjelle
1988);
) 140 / per os ( 5%-
ACYCLOVIR
5-10% ), 3-5
70 / per os (Mount 1989).
: ) 50 / 30-60 12
(Kirk 1986).
-
( ):
1) ( );
2) ,
( );
3) -
( );
|
|
|
4) ,
.
- .
/ / FDA / - : . :
10% ( ) (100 /) 20% (200 /) 4 , 10 30 , , Mucomyst (Apo-thecon); Mucosil -10 (Dey Labs), Mucosil -20 (Dey Labs), Generic (Rx).
ACETYLSALICYLIC ACID ( ) - . ASPIRIN ()
ACTH () -
. CORTICOTROPIN ()
ACTIVATED CHARCOAL ( ) - . CHARCOAL, ACTIVATED ( )
ACYCLOVIR -
- - ( ACV ), , . 1,3 1 . 1 100
. 7,4 t=37 C , 2,5 / . 4,2 .
/ / - . , . .
, . , , . 50-100 25 24 . , (, , ). , -, , , . , . , , . (, Handbook on Injectable Drugs by Trissel; . ).
- , ( I II), , - . , , .
/ - . , .
- ( 20%), -
. - , , . . , , , 3 . , , .
/ - ( / ) , , , .
|
|
|
, - . , , , .
/ - , (). , .
, , , , , .
/ - - . , , , .
- / . ( ).
- :
(Pacheco):
) 80 / per os 8 40 / 8 / ( -
_______________ ACYCLOVIR / ALBENDAZOLE 19
72 , ) (Oglesbee and Bishop 1994b); ) 80 / 1 per os, 50 4 7-14 (Jenkins 1993).
:
( / ), , :
) 1 200 per os 4 . . . - , (Olivero 1994).
-
1) ,
(, ),
/ ;
2) : .
/ / FDA / - : . :
400 800 ; Zovirax , (Glaxo Wellcome), generic (Rx).
200 , 400 800 , Zovirax (Glaxo Wellcome), generic (Rx).
: 200 /5 , Zovirax (Glaxo Wellcome) (Rx).
( / ), 500 / ( ) 10 ; 1000 / ( ) 20 ; Zovirax (Glaxo Wellcome); (Rx).
.
ALBENDAZOLE-
- - -. 265. , .
ALBENDAZOLE
/ / -
|
|
|
(15-30 ); . .
/ - , : Ostertagia ostertagi, Haemon - chus spp., Trichostrongylus spp., Nematodius spp., Coo - peria spp., Bunostomum phlebotomum, Oesphagosto - mum spp., Dictacaulus spp., Fasciola hepatica (), Moniezia spp. , .
, Paragonimus kellicotti. -. , FUaroides.
1984 -, - - .
- , . , , . 47% , , 9 .
, , . 20 .
/ - . 45 45 . , - .
.
/ - ,
, .
50 / 2 .
Paragonimus , , .
/ - 300 / ( 30 ) 200 / - . 45 / ( 4,5 ) . , 100 // 14-21 , , - .
- . . .
- :
FUaroides hirthi:
) 50 / 12 per os 5 ,
21 .
,
(Hawkins, Ettinger, and Suter
1989);
) 25 / per os 12 5 ;
2 (
Osl & ais osleri) (Reinemeyer 1995).
FUaroides osleri (
Oslerus osleri):
) 9,5 / 5 25 / per os 2 5 . 2 (Todd, Paul, and DiPietro 1985).
Capillaria plica:
a) 50 / 12 10-14 . (Brown and Barsanti 1989).
Paragonimus kellicotti:
) 50 / per os 21
(Roberson 1988b);
) 30 / 1 12 (Todd,
Paul, and DiPietro 1985);
) 25 / per os 12 14
(Reinemeyer 1995).
Giardia:
